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Test Code DIC Disseminated Intravascular Coagulation (DIC) Screen

Additional Codes

EPIC LAB4076

Purpose

The Disseminated Intravascular Coagulation (DIC) screen is a battery of tests consisting of PTINR, APTT, Fibrinogen, D-Dimer, platelet count, and peripheral smear for schistocytes. This battery of tests provides comprehensive testing to determine if intravascular clotting or hemolytic processes are occuring in vivo in the patient.

Methodology

  • ACL TOP 350
  • Sysmex XN-2000

Sample Type

Preferred Sample Type

Light blue (Plasma) AND Lavendar top (Whole blood)

 Centrifuge: Yes (Light Blue top only)

Specimen Minimum Volume

1.5 mL - Blue top

1 mL - Lavendar top

Specimen Stability

Temperature Time
Ambient (18-25°C) (store) 4 hours
Refrigerated (2-8°C) N/A
Frozen (<-20°C) N/A

NOTE: Separate plasma from cells within 2 hours

Reference Ranges

Test Normal Range Technical Range Therapeutic Range Critical Value
PT 9.4 - 12.5 sec 8.0 - 320.0 sec    
INR 0.80 - 1.10 0.70 - 28.30 2.00 - 3.00 >4.49
APTT 25.1 - 36.5 sec 16.0 - 400.0 sec   >170.0 sec
Fibrinogen 200 - 393 mg/dL 35 - 1,200 mg/dL    
D-Dimer <500 ng/mL 215 - 128,000 ng/mL   >500 ng/mL
Platelets 150 - 400 109/L 0.00 - 4,938 109/L   <10 or >998 109/L

Peripheral Smear for Schistocytes
None Seen

Rejection Criteria

  • Underfilled/Overfilled specimen (Blue top)
  • Clotted specimens
  • Specimens outside of stability limits

Availability

Performed STAT
24/7 Yes

 

Performing Laboratory

MultiCare Yakima Memorial Hospital Laboratory

Lab Department

Hematology

CPT Code

85610

85730

85379

85384

85049

85008

LOINC

5902-2      PT Coag (PPP) [Time]

6301-6      INR Coag (PPP) [Relative time]

14979-9    aPTT Coag (PPP) [Time]

3255-7      Fibrinogen Coag (PPP) [Mass/Vol]

48065-7    Fibrin D-dimer FEU (PPP) [Mass/Vol]

777-3        Platelets Auto (Bld) [#/Vol]

800-3        Schistocytes LM QI (Bld)

 

 

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