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Test Code FIBRIN Fibrinogen

Additional Codes

EPIC LAB4091

Purpose

When unexplained bleeding or abnormal clotting occurs, it may be of clinical importance to quantitate fibrinogen. Fibrinogen is also a useful marker in the evaluation of several disease states including Disseminated Intravascular Coagulation (DIC), liver disease, and inflammatory diseases.

 

Source: HemosIL Q.F.A. Thrombin (Bovine) PN 0020301800 IFU

Methodology

The fibrinogen in the diluted test sample is converted to fibrin by the addition of an excess of thrombin and the resulting clotting time value is measured. The log of the clotting time value is inversely proportional to the log of the fibrinogen concentration. A fibrinogen reference curve is plotted from the clotting time results of the known referenced plasma dilutions having different fibrinogen values. The concentration of fibrinogen in patient plasma samples is determined by comparing clotting time values to the reference curve.

Sample Type

Preferred Sample Type
Light blue top - Na Citrate Plasma

Centrifuge: Yes 

Specimen Minimum Volume

0.5 mL

 

NOTE: Na Citrate Blue top tubes require that the tube is filled adequately to maintain the 9:1 blood to anticoagulant ratio.

Specimen Stability

Temperature Time
Ambient (18-25°C) (store) 8 hours
Refrigerated (2-8°C) N/A
Frozen (-20°C) 14 days
Frozen (<-70°C) 6 months

NOTE: Separate plasma from cells within 2 hours

Reference Ranges

Normal Range
200 - 393 mg/dL

 

 

Technical Range
35 - 1,200 mg/dL

 

Rejection Criteria

  • Clotted samples
  • Underfilled/Overfilled samples

Availability

Performed STAT
24/7 Yes

 

Performing Laboratory

MultiCare Yakima Memorial Hospital Laboratory

Lab Department

Hematology

CPT Code

85384

LOINC

3255-7 Fibrinogen Coag (PPP) [Mass/Vol]