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Test Code FE Iron/Total Iron Binding Capacity

Additional Codes

EPIC LAB4128

Purpose

Alterations in iron and total iron binding capacity levels result from changes in iron intake, absorption, storage, and release mechanisms. Such changes are indicative of a wide range of dysfunctions including anemias, nephrosis, cirrhosis and hepatitis. Both iron and total iron binding capacity measurements are important for definitive diagnosis because they are interrelated.

 

Source: Beckman Coulter Unicel, FE IFU. REF #467910 12/22/15

Methodology

Timed-endpoint (Beckman Coulter UniCel DxC 660i)

Sample Type

Preferred Sample Type
Yellow top - Serum

 

Acceptable Sample Type(s)
Red top - Serum
Light green top - Plasma

Centrifuge: Yes

Specimen Minimum Volume

0.5 mL

Specimen Stability

Temperature Time
Ambient (18-25°C) 8 hours
Refrigerated (2-8°C) (store) 48 hours
Frozen (-15 to -20°C) 1 month

Separate plasma or serum from cells within 2 hours. 

Reference Ranges

Iron

Normal Range
0 - 11 months 100 - 250 ug/dL
1 - 12 years  40 - 100 ug/dL
Adult Male 45 - 190 ug/dL
Adult Female* 30 - 180 ug/dL

 

Technical Range
5 - 500 ug/dL

 


Total Iron Binding Capacity

Normal Range
Male 250 - 450 ug/dL
Female* 260 - 490 ug/dL

 

 

Transferrin

Normal Range
Male 180 - 329 mg/dL
Female 192 - 382 mg/dL

 

 

Percent Saturation (Iron)

Normal Range
Male 20 - 50 %
Female 15 - 50 %

 

*Oral contraceptives may elevate iron and/or total iron binding capacity values. 

Rejection Criteria

Hemolysis 1+ or greater
Icteric N/A
Lipemia 3+ ultracentrifuge

EDTA, Sodium citrate, and potassium oxalate specimens.

Availability

Performed STAT
24/7 Yes

 

Performing Laboratory

MultiCare Yakima Memorial Hospital Laboratory

Lab Department

Chemistry

CPT Code

83540

83550

84466

LOINC

2498-4 Iron [Mass/Vol]

2500-7 Iron binding capacity [Mass/Vol]

3034-6 Transferrin [Mass/Vol]

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