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HelpTest Code VPA Valproic Acid (Depakote) Level
Additional Codes
| EPIC | LAB4220 |
Synonyms
- Divalproex
- Valproate
- Dipropylacetic acid
Clinical Significance
Valproic Acid is an anticonvulsant drug. It is indicated for the treatment of absence (petite mal), generalized tonic-clonic and myclonic seizures. Valproic Acid therapy is monitored for suspected inadequate dose or toxicity.
Source: Beckman Coulter Unicel, VPA IFU. REF #467995 12/23/15
Methodology
Particle enhanced turbidimetric inhibition immunoassay (Beckman Coulter UniCel DxC 660i)
Sample Type
| Preferred Sample Type | |
|---|---|
| Light green top - Plasma | |
| Acceptable Sample Type(s) | |
|---|---|
| Dark green top - Plasma | |
| Yellow top - Serum | |
| Red top - Serum | |
Centrifuge: Yes
Specimen Minimum Volume
0.3 mL
Specimen Stability
| Temperature | Time |
|---|---|
| Ambient (18-25°C) | 8 hours |
| Refrigerated (2-8°C) (store) | 48 hours |
| Frozen (-15 to -20°C) | 1 month |
Separate plasma or serum from cells within 2 hours.
Reference Ranges
| Therapeutic Range |
|---|
| 50.0 - 100.0 ug/mL |
| Critical Value |
|---|
| >150.0 ug/mL |
| Technical Range |
|---|
| 10.0 - 150.0 ug/mL |
Rejection Criteria
| Hemolysis | N/A |
|---|---|
| Icterus | N/A |
| Lipemia | N/A |
Availability
| Performed | STAT |
|---|---|
| 24/7 | Yes |
Performing Laboratory
MultiCare Yakima Memorial Hospital Laboratory
Lab Department
Chemistry
CPT Code
80164
LOINC
4086-5 Valproate [Mass/Vol]