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HelpTest Code TOBT Tobramycin Level, Trough
Additional Codes
| EPIC | LAB5327 |
Synonyms
- Tobrex
- Nebcin
- Bethkis
Clinical Significance
Tobramycin is an aminoglycoside antibiotic typically used to treat Gram-negative infections and is monitored for effectiveness of the dose and possible nephrotoxicity.
Source: Beckman Coulter Unicel, TOB IFU. REF #467983 5/6/15
Methodology
Particle enhanced turbidimetric inhibition immunoassay (Beckman Coulter UniCel DxC 660i)
Sample Type
| Preferred Sample Type | |
|---|---|
| Light green top - Plasma | |
| Acceptable Sample Type(s) | |
|---|---|
| Dark green top - Plasma | |
| Yellow top - Serum | |
| Red top - Serum | |
Centrifuge: Yes
Specimen Minimum Volume
0.3 mL
Specimen Stability
| Temperature | Time |
|---|---|
| Ambient (18-25°C) | 8 hours |
| Refrigerated (2-8°C) (store) | 48 hours |
| Frozen (-15 to -20°C) | 1 month |
Separate plasma or serum from cells within 2 hours.
Reference Ranges
| Therapeutic Range |
|---|
| 1.0 - 2.0 ug/mL |
| Critical Values |
|---|
| >2.0 ug/mL |
| Technical Range |
|---|
| 0.5 - 12.0 ug/mL |
Rejection Criteria
| Hemolysis | N/A |
|---|---|
| Icterus | N/A |
| Lipemia | N/A |
Reject sodium heparanized plasma samples.
Availability
| Performed | STAT |
|---|---|
| 24/7 | Yes |
Performing Laboratory
MultiCare Yakima Memorial Hospital Laboratory
Lab Department
Chemistry
CPT Code
80200
LOINC
4059-2 Tobramycin trough [Mass/Vol]