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Mayo Clinic Laboratories

Test Code THEO Theophylline Level

Additional Codes

EPIC LAB6490

Synonyms

  • Elixophylline
  • Theochron
  • Aminophylline
  • Choledyl
  • Oxtriphylline
  • Slophylline
  • Tedral
  • Theodur

Clinical Significance

Theophylline is administered for the treatment of bronchial asthma and is monitored for possible toxicity, and as a guide for acute and maintenance therapy.

 

Source: Beckman Coulter Unicel, THE IFU. REF #469126 4/20/15

Methodology

Particle enhanced turbidimetric inhibition immunoassay (Beckman Coulter UniCel DxC 660i)

Sample Type

Preferred Sample Type
Light green top - Plasma

 

Acceptable Sample Type(s)
Dark green top - Plasma
Yellow top - Serum
Red top - Serum

Centrifuge: Yes

Specimen Minimum Volume

0.3 mL

Specimen Stability

Temperature Time
Ambient (18-25°C) 8 hours
Refrigerated (2-8°C) (store) 48 hours
Frozen (-15 to -20°C) 1 month

Separate plasma or serum from cells within 2 hours.

Reference Ranges

Therapeutic Range
10 - 20 ug/mL

 

Critical Value
>20 ug/mL

 

Technical Range
2.0 - 40.0 ug/mL

 

Rejection Criteria

Hemolysis N/A
Icterus N/A
Lipemia N/A

Reject sodium heparanized plasma samples.

Availability

Performed STAT
24/7 Yes

 

Performing Laboratory

MultiCare Yakima Memorial Hospital Laboratory

Lab Department

Chemistry

CPT Code

80198

LOINC

4049-3 Theophylline [Mass/Vol]