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HelpTest Code TCRYO Transfuse Cryoprecipitate
Clinical Significance
Cyroprecipitated antihaemophilic factor (cryo) is used in the control of bleeding associated with Facto VIII deficiency. Its use is also indicated for von Willebrand's disease and for replacement of fibrinogen or Factor XIII. Cryo may also be incorporated during a massive transfusion protocol to replace coagulation factors lost through rapid hemorrhage.
Cryoprecipitate contains coagulation Factor VIII, Facor XIII, fibrinogen, vWF, and fibronectin. Each unit of cryo should contain 80 or more Factor VIII units and at least 150 mg of fibrinogen in less than 15 mL plasma. Single unit cryo can also be used in the preperation of fibrin sealant in some surgical cases.
Selection of Unit
ABO grouping may be disregarded and no crossmatch band or patient specimen is required. It is not assigned as a type specific component since the amount of anti-A and anti-B is ~1% of the total from the unit of plasma.
Unit Storage
Frozen: Stored at -20°C
Thawed: Individual and pooled units should be transfused within 2 hours for maximum patient benefit, but may still be transfused within 6 hours of thawing.
Unit Preparation
Cryo is kept frozen and is thawed in five to ten minutes using a 37°C water bath.
Availability
| Performed | STAT |
|---|---|
| 24/7 | Yes |
Performing Laboratory
MultiCare Yakima Memorial Hospital Laboratory
Lab Department
Blood Bank
HCPCS Code
P9012
LOINC
51881-1 Transfuse cryoprecipitate units (BPU) [#]