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HelpTest Code MONO Infectious Mononucleosis
Additional Codes
| EPIC | LAB4242 |
Clinical Significance
The Sure-Vue Color-Mono test is used to detect heterophile antibodies associated with infectious mononucleosis (IM) caused by Epstein-Barr virus. IM heterophile antibodies may be present as early as the fourth day of illness, aslmost always are present by the twenty-first day of illness, and may persist for several months thereafter.
Source: Sure-Vue Color Mono Test IFU 3800-2973. Rev. 05/09
Methodology
The mononucleosis test is a rapid color enhanced slide test for detection of heterophile antibodies associated with IM. This test utilizes a disposable card, guinea pig kidney antigen, and specially treated horse erythrocytes (color-enhanced) to increase specificity and sensitivity, and to enhance readability of the test. In the presence of IM heterophile antibodies, horse erythrocytes agglutinate to form visible clumps.
Sample Type
| Preferred Sample Type | |
|---|---|
| Yellow top - Serum | |
| Acceptable Sample Type(s) | |
|---|---|
| Red top - Serum | |
| Lavender top - EDTA Plasma | |
Centrifuge: Yes
Specimen Minimum Volume
0.5 mL
Specimen Stability
| Temperature | Time |
|---|---|
| Ambient (18-25°C) | |
| Refrigerated (2-8°C) (store) | 24 hours |
| Frozen (<-20°C) | >24 hours |
Reference Ranges
| Normal |
|---|
| Negative |
| Abnormal |
|---|
| Positive |
Rejection Criteria
| Hemolysis | 4+, reject |
|---|---|
| Icterus | N/A |
| Lipemia | N/A |
- Heparinized specimens
Availability
| Performed | STAT |
|---|---|
| 24/7 | Yes |
Performing Laboratory
MultiCare Yakima Memorial Hospital Laboratory
Lab Department
Blood Bank
CPT Code
86308
LOINC
5213-4 Heterophile Ab LA QI (S)